Estec Kenya > Brands > Shimadzu > Chromatography

Chromatography

Shimadzu HPLC systems deliver precise and reliable separation and quantification of chemical compounds, making them ideal for research, quality control, and routine analytical labs. Built for accuracy, reproducibility, and compliance, these systems combine robust construction with flexible configurations for both routine testing and advanced workflows.

With high precision, exceptional sensitivity, and reliable performance, Shimadzu HPLC systems are engineered to manage high-throughput analytical workflows efficiently. A defining advantage of this platform is its modular architecture, which supports flexible detector and column configurations. Multiple detectors—including UV-Vis, Photodiode Array (PDA), Fluorescence, and Refractive Index—can be configured in series or parallel, enabling comprehensive molecular characterization from a single injection and maximizing the informational yield of each sample. For advanced impurity profiling or trace residual analysis, the system can be expanded to an LC-MS configuration, delivering mass spectral data required for definitive compound identification.

To maintain data integrity in regulated environments, the system’s intuitive software is fully compliant with 21 CFR Part 11, incorporating secure electronic signatures and automated audit trails that document every user interaction. The software also integrates seamlessly with Laboratory Information Management Systems (LIMS), enabling bi-directional transfer of sample sequences and analytical results, thereby minimizing manual transcription errors. In addition, the platform incorporates advanced AI-driven capabilities, such as “AI Peak Deconvolution” for resolving overlapping chromatographic signals and “Analytical Intelligence” for automated mobile phase monitoring and system self-diagnostics. These features allow laboratories to tailor analytical configurations to specific research or industrial applications while ensuring adherence to global regulatory requirements

IndustryPrimary ApplicationSpecific Chemical Targets
PharmaceuticalCompliance & SafetyAPIs, Impurity Profiles, Residual Solvents, Degradants.
Food & BeverageQuality & SafetyPesticides, Vitamins, Mycotoxins, Caffeine, Illegal Additives.
EnvironmentalPollutant MonitoringPFAS ("Forever Chemicals"), Herbicides, Endocrine Disruptors.
Biotech/ClinicalDiagnosticsProteins, Biomarkers, Newborn Metabolic Screening, HbA1c.
ForensicsLegal EvidenceToxicology (drugs/poisons in blood), Explosive Residue.
Academic/IndustrialDiscoveryNew molecule synthesis, Proteomics, Reaction monitoring.

Available Models:

Shimadzu UHPLC systems are engineered to deliver faster separations, higher resolution, and superior analytical sensitivity for laboratories requiring high throughput without compromising accuracy. Designed for advanced analytical workflows, these systems operate at ultra-high pressures of up to 130 MPa, enabling the use of sub-2 µm particle columns to achieve sharper peak resolution and significantly reduced run times. Their robust construction and flexible configurations make them suitable for both high-speed routine analysis and complex research applications.

UHPLC systems support a wide range of laboratory applications, including trace impurity profiling, metabolite and biomolecule analysis, pharmaceutical method development, stability testing, food contaminant screening, and environmental monitoring. They are also widely used in academic and industrial research laboratories where rapid and high-resolution separations are required for complex sample matrices.

These systems offer exceptional chromatographic performance through precise solvent delivery, low carryover autosamplers, and highly sensitive detection options. Advanced automation, intelligent system control, and user-friendly software allow laboratories to optimize workflows while maintaining regulatory compliance and data integrity. High durability components ensure dependable performance even under continuous high-pressure operation, making UHPLC systems ideal for high-volume quality control environments.

Industries Served:

Pharmaceutical manufacturing, biotechnology, food & beverage industry, environmental laboratories, chemical & petrochemical industries, academic and research institutions, and commercial testing laboratories.

Shimadzu LC‑MS/MS systems combine high‑performance liquid chromatography (UHPLC) with advanced mass spectrometry to deliver fast, sensitive, and accurate analysis of small molecules, biomolecules, and complex sample matrices. Featuring rapid polarity switching (up to 15,000 transitions/sec), high ion transmission efficiency, and optimized ion optics, these platforms provide exceptional quantification performance, even at trace levels. The systems are designed for robust, reproducible operation in both research and regulated quality control environments.

These systems are widely used in pharmaceutical drug development and bioanalysis, environmental contaminant monitoring, food safety testing, forensic toxicology, clinical research, and chemical analysis. Common applications include multi‑residue pesticide screening, metabolite identification, pharmacokinetic studies, and trace impurity quantification. Shimadzu’s LC‑MS/MS platforms deliver low limits of detection (sub‑ppt levels), wide linear dynamic ranges (8+ orders of magnitude), and rapid data acquisition, making them highly suitable for high‑throughput laboratories.

Key performance features include:

  • UFswitching™: 5 ms polarity switching.
  • UFscanning™: 30,000 u/sec scan speeds.
  • UF-MRM™: 555 channels per second.
  • UFsweeper™: High-speed collision cell technology.
  • UF-Qarray™: High-sensitivity ion guide.
  • UF-Lens™: Optimized ion optics.

 Software & Workflow Features

  • LabSolutions Insight™: High-throughput multi-analyte software for rapid data review.
  • Automated QA/QC Flagging: Over 75 user-defined criteria (e.g., retention time, ion ratio, concentration) that highlight outliers via color-coded “Review by Exception.”
  • Intuitive Interface: Configurable, dockable windows with sample-centric or compound-centric views to simplify navigation of large datasets.
  • Automated Method Development: Dedicated tools like LabSolutions MD (using Analytical Quality by Design) and Smart MRM that automatically optimize acquisition windows and parameters.
  • Peakintelligence™: A deep-learning AI algorithm that automates peak integration, reducing manual processing time by up to 75%.
  • Regulatory Compliance: Full support for 21 CFR Part 11, featuring centralized data management, audit trails, and electronic signatures via LabSolutions DB/CS.
  • Customizable Reporting: Automated report generation tools that streamline the transition from raw data to final, compliant documentation.

Industries Served:

Pharmaceuticals and biotech, environmental and water testing, food & beverage safety, clinical and forensic labs, chemical & petrochemical industries, commercial testing laboratories and regulatory agencies requiring high‑precision quantification and compound characterization.

Shimadzu Gas Chromatography (GC) systems are designed to deliver precise and reliable analysis of volatile and semi-volatile compounds across research and routine quality control laboratories. Built for accuracy, stability, and long-term operational reliability, these systems incorporate advanced temperature control, highly stable flow regulation, and sensitive detection technologies to ensure reproducible analytical results even in demanding testing environments.

GC systems are widely used for applications such as residual solvent analysis, petrochemical composition testing, environmental VOC monitoring, food flavor and contaminant analysis, forensic investigations, and industrial chemical quality control. Their versatility makes them essential tools in laboratories requiring consistent analysis of gaseous and volatile samples.

Shimadzu GC platforms offer excellent analytical performance through fast oven heating and cooling cycles, precise electronic pressure and flow control, and highly sensitive detector options including FID, TCD, ECD, and specialized configurations. Wide oven temperature ranges, automated sampling options, and intelligent software integration allow laboratories to optimize throughput while maintaining compliance with international analytical standards. Robust hardware design ensures dependable performance in high-sample-volume environments.

Industries Served:

Pharmaceutical Manufacturing, Petrochemical and Energy industries, Environmental testing laboratories, Food & Beverage production, Chemical Industries, Commercial Testing labs and Regulatory testing agencies that require reliable analysis of volatile compounds.

Shimadzu GC–MS and GC–MS/MS systems combine high-performance gas chromatography with sensitive mass spectrometric detection to deliver accurate, reproducible, and ultra-sensitive analysis of volatile and semi-volatile compounds. These systems are engineered for demanding research, quality control, and regulatory testing laboratories, providing reliable performance even in high-throughput workflows.

GC–MS/MS platforms are widely used for residual solvent analysis, environmental pollutant monitoring, petrochemical testing, food flavor and contaminant analysis, forensic toxicology, and chemical quality control. By integrating precise oven temperature control, rapid temperature programming, and highly sensitive detectors, these systems enable laboratories to achieve low detection limits, wide dynamic ranges, and consistent quantification across complex sample matrices.

Core Features

  • UF-MRM™: 800 transitions/sec
  • ASSP™ (Scan Speed): 20,000 u/sec
  • UFsweeper™: High-speed collision cell
  • Minimum Dwell Time: < 0.5 ms
  • Minimum Event Time: 3 ms
  • Off-Axis Ion Optics: High S/N ratio
  • Shielded Ion Source: Thermal stability
  • Smart MRM™: Automated method optimization
  • LabSolutions Insight™: Automated flagging and data review
  • Peakintelligence™: AI-driven peak integration
  • Active Time Management™: Real-time readiness tracking
  • Smart Database Series: Pre-optimized application files

 Software & Analytical Intelligence Features

  • LabSolutions Insight™: Multi-analyte software designed for high-speed review of massive datasets.
  • Automated Flagging: Color-coded system that highlights outliers in ion ratios, retention times, and concentration to streamline quality control.
  • Smart MRM™: Automatically optimizes acquisition windows and dwell times based on elution patterns to maximize data points per peak.
  • Peakintelligence™: A deep-learning AI engine that performs automated peak integration, reducing manual processing time and human error.
  • Smart Database Series: Pre-optimized method files for pesticides, forensics, and environmental analysis that align with UF hardware capabilities.
  • Active Time Management™: Real-time tracking of instrument status (e.g., cooling/startup times) to minimize laboratory downtime.
  • Easy sTop: Tool-free maintenance (ClickTek) that allows users to replace liners or septa without venting the vacuum, maximizing “active” uptime.

 Industries Served: Pharmaceuticals, Environmental laboratories, Petrochemical and Chemical Industries, Food & Beverage, Forensic and Clinical labs, and Commercial Testing Laboratories that require precise and reliable analysis of volatile compounds.

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