Description
LCMS-8060 NX
LCMS-8050
LCMS-8045
LC-MS/MS Systems – Liquid Chromatography Mass Spectrometry
Shimadzu LC-MS/MS systems are designed for non-volatile, polar, and thermally labile compounds, making them essential for biological and pharmaceutical applications.
- Typical Configuration: UHPLC (e.g., Nexera) coupled with triple quadrupole MS
Key Systems
- LCMS-8060 NX – ultra-fast, high-sensitivity triple quadrupole LC-MS/MS for high-throughput quantitative analysis
- LCMS-8050 – high-performance LC-MS/MS system balancing sensitivity and speed for routine and advanced workflows
- LCMS-8045 – reliable LC-MS/MS platform for routine quantitative analysis with strong sensitivity
Strengths:
- High sensitivity for trace-level quantitation
- Excellent selectivity using MRM (Multiple Reaction Monitoring)
- Minimal sample preparation compared to GC-based methods
Applications: biomolecules, pharmaceuticals, metabolites, pesticides
GC-MS/MS Systems – Gas Chromatography Mass Spectrometry
Shimadzu GC-MS/MS systems are optimized for volatile and semi-volatile compounds, providing highly reproducible separations and strong spectral libraries for identification.
- Typical Configuration: GC (e.g., Nexis GC) coupled with single or triple quadrupole MS
Key Models
- GCMS-TQ8050 NX – ultra-high sensitivity triple quadrupole GC-MS/MS for trace-level quantification in complex matrices s
- GCMS-TQ8040 NX – high-performance GC-MS/MS system for routine to advanced quantitative analysis
- GCMS-QP2050 – single quadrupole GC-MS system for reliable qualitative and quantitative workflows
Strengths:
- High chromatographic resolution for volatile compounds
- Established spectral libraries for confident identification
- Strong performance in complex environmental and petrochemical samples
Applications: VOCs, hydrocarbons, residual solvents, environmental pollutants
GCMS-TQ8050 NX
GCMS-TQ8040 NX
GCMS-QP2050
Core Characteristics & Performance
- High Sensitivity Detection – enables identification at trace and ultra-trace levels
- Fast Scan Speeds – supports accurate detection of narrow GC peaks
- High Selectivity (MRM capability) – eliminates interferences in complex matrices
- Stable Ion Optics & Source Design – ensures long-term reproducibility and minimal drift
Wide Mass Range & Dynamic Range – suitable for both small molecules and complex mixtures
Smart AI Features & Automation
Shimadzu MS systems incorporate advanced AI and data-driven automation to streamline workflows:
- Peakintelligence™ (AI Integration) – automated peak integration with high accuracy, reducing analyst variability
- Smart SIM / Smart SIM+ – automatic optimization of monitoring conditions
- Smart Databases – built-in libraries with optimized acquisition parameters
- Automated Method Development – reduces setup time and expertise requirements
- LabSolutions Insight – advanced data processing, batch analysis, and reporting
- Analytical Intelligence – system monitoring, maintenance alerts, and workflow optimization
Operational Advantages
- Reduced Manual Data Processing through AI-assisted analysis
- High Throughput Capability for large sample batches
- Minimal Downtime with easy maintenance and robust design
- Confident Identification via spectral matching and databases
Industries Served
Shimadzu MS systems are critical across:
- Pharmaceutical – drug development, impurity analysis, bioanalysis
- Clinical & Life Sciences – biomarker discovery, metabolomics
- Food & Beverage – pesticide residue and contaminant detection
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